Search results for "quantitative genetic"
showing 10 items of 25 documents
Genetic correlation between resistance to oxidative stress and reproductive life span in a bird species.
2010
Evolutionary theories propose that aging is the result of a trade-off between self-maintenance and reproduction, and oxidative stress may play a crucial role in such a trade-off. Phenotypic manipulations have revealed that a high investment in reproduction leads to a decline in the organism's resistance to oxidative stress, which could in turn accelerate aging. Here, by using quantitative genetic analyses as a tool to disentangle genetic effects from phenotypic variances, the relationship between resistance to oxidative stress at sexual maturity and two key reproductive life-history traits (i.e., number of breeding events during life and age at last reproduction) was analyzed in cross-foste…
Behavior adaptation and selection.
2010
6 pages; The evolutionary approach to behavior is concerned with the evolutionary origin and adaptive function of behavioral traits. Like any other part of the phenotype, behavior can be shaped by natural selection to produce adaptations. However, behavior often shows large phenotypic variation and flexibility, and can be both – subject to selection and a major agent of selection. Therefore, the study of adaptation and evolution of behavior is a particularly complex one, involving a wide range of methodologies and techniques, including mathematical modeling, comparative methods, phenotypic engineering, quantitative genetics, genetic dissection, and artificial selection.
DSM-IV Combined Type ADHD Shows Familial Association With Sibling Trait Scores
2008
Contains fulltext : 69060.pdf (Publisher’s version ) (Closed access) Attention deficit hyperactivity disorder (ADHD) is a discrete clinical syndrome characterized by the triad of inattention, hyperactivity, and impulsivity in the context of marked impairments. Molecular genetic studies have been successful in identifying genetic variants associated with ADHD, particularly with DSM-IV inattentive and combined subtypes. Quantitative trait locus (QTL) approaches to linkage and association mapping have yet to be widely used in ADHD research, although twin studies investigating individual differences suggest that genetic liability for ADHD is continuously distributed throughout the population, u…
Physical Activity and Academic Performance: Genetic and Environmental Associations
2019
Introduction Physical activity and academic performance are believed to be associated. Though both traits are partially heritable, it remains unclear whether these traits also share a genetic and/or environmental background in common. We aimed to examine to what extent leisure time physical activity and academic performance share genetic and environmental effects from early adolescence to young adulthood. Methods Participants were Finnish twins (2543-2693 individuals/study wave) who reported their leisure-time physical activity at ages 12, 14, 17, and 24 yr. Academic performance was assessed with teacher-reported grade point averages at ages 12 and 14 yr and by self-reported educational lev…
Quantitative Genetics of the Aging of Reproductive Traits in the Houbara Bustard
2015
International audience; Do all traits within an organism age for the same reason? Evolutionary theories of aging share a common assumption: the strength of natural selection declines with age. A corollary is that additive genetic variance should increase with age. However, not all senescent traits display such increases suggesting that other mechanisms may be at play. Using longitudinal data collected from more than 5400 houbara bustards (Chlamydotis undulata) with an exhaustive recorded pedigree, we investigated the genetics of aging in one female reproductive trait (egg production) and three male reproductive traits (courtship display rate, ejaculate size and sperm viability), that displa…
Leisure-time physical activity and DNA methylation age-a twin study.
2018
Background Epigenetic clocks may increase our understanding on human aging and how genetic and environmental factors regulate an individual aging process. One of the most promising clocks is Horvath’s DNA methylation (DNAm) age. Age acceleration, i.e., discrepancy between DNAm age and chronological age, tells us whether the person is biologically young or old compared to his/her chronological age. Several environmental and lifestyle factors have been shown to affect life span. We investigated genetic and environmental predictors of DNAm age in young and older monozygotic (MZ) and dizygotic (DZ) twins with a focus on leisure time physical activity. Results Quantitative genetic modeling revea…
Quantitative genetics of sexual display, ejaculate quality and size in a lekking species.
2013
9 pages; International audience; The investment into extravagant sexual display and competitive sperm are two essential components of pre- and post-copulatory sexual selection. Even though the selective forces acting on sexual display and sperm characteristics have been extensively studied in recent years, the genetic architecture underlying the expression of these traits has been rarely explored. Here, we estimated the genetic variances and covariances of traits linked with ejaculate size and quality, and sexual display in the houbara bustard (Chlamydotis undulata undulata, Jacquin 1784). Using a very large pedigree-based data set, we show that sexual signalling and ejaculate size (but not…
Combining molecular microbial ecology with ecophysiology and plant genetics for a better understanding of plant-microbial communities' interactions i…
2013
18 pages; International audience
Composantes de l’architecture racinaire de la plante associées aux QTL de résistance à Aphanomyces euteiches dans des lignées quasi-isogéniques de po…
2021
Pea (Pisum sativum L.) is the most cultivated seed legume in the world after common bean. But it issubject to a disease against which there is no effective treatment, root rot caused by Aphanomyceseuteiches. The only sustainable solution to control A. euteiches is genetic control. Previous studies haveidentified a positive correlation between the root area or biomass of lines and their level of resistance toroot rot caused by A. euteiches. The aim of the internship, which was part of the research project"Diversification and Combination of Aphanomyces Resistance QTLs in Protein Pea (DORA)", was toidentify whether changes in the components of the root system architecture of pea are induced by…
Leisure-Time and Occupational Physical Activity Associates Differently with Epigenetic Aging
2021
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